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Whilst low-depend MBL not often progresses to CLL, high-depend MBL progresses to CLL necessitating therapy in a amount of one% to two% every year. Substantial-depend MBL is distinguished from Rai 0 CLL depending on if the B-mobile depend is over or underneath five × 109/L. Even though men and women with each significant-depend MBL and CLL Rai stag